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Multiskan Ease Absorbance Microplate Reader

The Thermo Scientific™ Multiskan™ Ease Absorbance Microplate Reader is a modern visible-range absorbance reader (400–760 nm) designed to simplify both routine and advanced microplate-based assays. It supports 96- and 384-well plate formats and features an intuitive 8-inch full-color touchscreen with built-in shaking and incubation for temperature-sensitive protocols. With straightforward SkanIt™ Software integration to make absorbance reading easy, fast, and smart.

Overview

Overview

The Thermo Scientific™ Multiskan™ Ease Absorbance Microplate Reader is a modern visible-range absorbance reader (400–760 nm) designed to simplify both routine and advanced microplate-based assays. It supports 96- and 384-well plate formats and features an intuitive 8-inch full-color touchscreen with built-in shaking and incubation for temperature-sensitive protocols. With straightforward SkanIt™ Software integration to make absorbance reading easy, fast, and smart.

For researchers performing ELISA, protein quantification, cytotoxicity, enzyme kinetics, and other absorbance assays, the Multiskan™ Ease enables reliability, flexibility, and ease of use. Its easyworkflow integration—covering data transfer, analysis, and reporting—enhances laboratory productivity without the need for additional training. Backed by near 50 years of trusted performance, the Multiskan™ Ease combines robust functionality with the confidence of the Thermo Scientific brand.

Applications

Multiskan™ Ease accommodates a comprehensive array of analytical and biological assays:

  • ELISA immunoassays- endpoint and kinetic formats
  • Protein quantification- Bradford, Lowry, BCA, and peptide assays
  • Endotoxin assays- chromogenic detection for quality control
  • Cell cytotoxicity and proliferation – alamarBlue™, PrestoBlue™, and CyQUANT™ assays
  • Enzyme kinetic assays- activity, inhibition, and rate studies
  • Growth curve analysis for microbial populations- population monitoring and turbidity analysis

Features

  • Large 8-inch full-color touch screen with user-friendly multi-language interface that streamlines assay setup, data review, and instrument control
  • Efficient white LED light source offers exceptional stability, energy efficiency, and extended lifetime operation
  • Enhanced optical design and precision thermal control enables accurate absorbance measurements, consistent plate-to-plate performance, and long-term instrument stability
  • Compatibility with both 96- and 384-well plates with and without lid, integrated shaking, and incubation up to 45°C
  • Redesigned easy-to-change 8-positions filter wheel and durable hard-coated optical filters (3 pre-installed: 405 nm, 450 nm and 620 nm) for long-lasting operation and low maintenance.
  • USB-C and USB-A connectivity for simple data transfer; fully compatible integration with automation platforms; cloud-ready architecture
  • Intuitive SkanIt software for streamlined workflow management and comprehensive data analysis
  • Dependable performance and reliable daily operation with proprietary optics and self-diagnostics

The instrument includes a 1-year standard warranty, with extended warranty coverage and IQ/OQ/IPV services available separately. Verification plates (Cat. No. 24072800 and 24072805) are available for routine performance qualification, enabling verification of photometric accuracy, precision, linearity, wavelength accuracy, and stray light. Additional optical filters can be purchased separately to support different assay requirements and expand application flexibility.

For Research Use Only. Not for use in diagnostic procedures.

Multiskan Ease Absorbance Microplate Reader

Reliable absorbance results, without complexity

Built on nearly 50 years of trusted Multiskan expertise, the Thermo Scientific Multiskan Ease Absorbance Microplate Reader helps laboratories generate reliable absorbance data quickly, with minimal setup, minimal training, and minimal maintenance.

Designed for routine absorbance assays, Multiskan Ease Absorbance Microplate Reader simplifies everyday workflows so you can focus on results, not instrument complexity. From simple assay setup to immediate data visibility, it supports common applications such as ELISA, cell viability, cytotoxicity, protein quantification and endotoxin testing.

With an intuitive touchscreen interface and preloaded, validated SkanIt Software protocols, lab users can run assays confidently from day one. And with LED-based optics, there’s no lamp replacement, reducing downtime and total cost of ownership. Engineered for straightforward operation and dependable performance, Multiskan Ease Absorbance Microplate Reader reflects Thermo Scientific’s commitment to quality, usability, and global service and support, helping laboratories meet day-to-day research and testing needs with confidence.

Why scientists choose Multiskan Ease Absorbance Microplate Reader

Simple absorbance workflows. Faster, more confident results.

Multiskan Ease Absorbance Microplate Reader reduces common frustrations in routine absorbance testing, complex setup, inconsistent data, long training times, and maintenance downtime. Designed to carry forward the proven and trusted reliability of the legacy Multiskan FC reader and delivers practical improvements that remove everyday barriers in the lab.

You can trust the results

Consistent, reproducible absorbance data

Stable LED optics and hard-coated filters deliver consistent readings across plates, runs, and users.

Reproducibility that holds up over time

Across plates, users, and studies

Controlled incubation and guided workflows maintain reliable results across users and studies.

Fast, repeatable setup

Get started in minutes

Preloaded, validated protocols reduce setup time and minimize user error.

Data is easy to interpret

From plate to answer, faster

Built-in curve fitting and automated reports simplify ELISA and routine data analysis.

High uptime, low maintenance

Ready when your experiments are

LED illumination eliminates lamp replacement, reducing downtime and total cost of ownership.

Easy for every user

Minimal training required

Touchscreen operation and guided software make onboarding fast for any lab member.

Backed by a platform labs trust

Thermo Scientific quality and support

Backed by global service, IQ/OQ options, and proven Multiskan performance.

Fits into modern lab workflows

Flexible and connected

Supports 96- and 384-well plates with incubation, shaking, and USB/Ethernet/cloud connectivity.

Specifications

Multiskan™ Ease Absorbance Microplate Reader (Cat. No. ME001000C)

Absorbance Range 400-760 nm
Cuvettes No
Detector Type Photodetector
Dimensions (L x W x H) 40 x 29.5 x 21.5 cm (15.7 x 11.6 x 8.5 in.)
Filters 8-position filter wheel, 3 pre-installed: 405 nm, 450 nm and 620 nm
Incubator Temperature Ambient +4° to 45°C
Interface Touchscreen or PC Control
Light Source LED
Measurement Speed Fast mode: ≤10 sec., Precision mode: ≤20 sec.
Measurement Technology Absorbance
Plate Type 96 and 384-well Plates
Product Type Microplate Reader
Quantity 1 Ea.
Read-out Range Up to 4 Abs
Reading Options Kinetic
Shaking Linear
Software Type SkanIt Software
Unit Size Each
Voltage 100/240 V
Warranty 1-year Standard
Wavelength Selection Filters
Weight (Metric) 10 kg

Technical specifications

FeatureSpecification
Overall dimensions (H x W X D) 215 x 295 × 400 mm (8.46 x 11.6 ×15.75 in)
Weight 10 kg (22.05 lb)
Operation conditions 10°C to 40°C; Maximum relative humidity 80% for temperatures up to 31°C. Decreasing linearly to 50% relative humidity at 40°C. Indoor use only
Mains power supply 100–240 Vac, 50/60 Hz, nominal.
Power consumption Max. 85 W, typical operation (without heating) 25 W
Noise <50 db (at a distance of 500 mm)
User interface Standalone use: 8-inch touch screen display PC control: SkanIt software
Connections 1 USB type A, USB 2.0 1 USB type B, USB 2.0 1 USB type C, USB 2.0 Ethernet port
Plate type 96-well and 384-well microplates, with or without lid, maximum total height 18 mm.

Absorbance

Light source White LED
Wavelength range 400–760 nm
Wavelength selection 8-position filter wheel (3 factory-installed, 5 optional)
Factory filters [1] 405 nm, 450 nm and 620 nm
Bandwidth (FWHM) 3–8 nm
Wavelength accuracy ±2 nm
Linearity (Absorbance), at 450 nm 0–3 Abs, 2.0%
Accuracy (Absorbance), at 450 nm ±(1.0% + 0.003 Abs) (0–3 Abs)
Precision (Absorbance), at 450 nm SD <0.005 Abs or CV <0.5%, whichever is greater
Turbidimetric sensitivity <5 FTU (formazine turbidimetric units)
Measurement speed [2] 96-well microplates Fast mode: ≤10 seconds Precision mode: ≤20 seconds

Incubator

Temperature range From ambient +4°C to 45°C (at room temperature 25°C)
Liquid warm-up time <40 minutes from 25°C to 37°C (96-well microplate, 200 µL water/well)
Mean temperature of wells at 37°C ±0.5°C
Plate temperature uniformity at 37°C <1.0°C

Shaker

Shaking mode Linear
Shaking speeds Low (5 Hz, amplitude 15 mm), medium (11 Hz, amplitude 3 mm), high (18 Hz, amplitude 1 mm)
Shaking type Continuous or pulsed

Documents

Videos

Absorbance, Redefined | Meet the New Multiskan Ease

Product information, images, documents and videos: Thermo Fisher Scientific. View on manufacturer website Source 2