Vios iDx CR 165 CO₂ Incubator – CTS Series

Overview

Overview

The Vios iDx certified cleanroom-compatible CO2 incubator is designed with both active particle control and rigorous cleaning capability in mind, setting the standard for cleanroom incubation. A Factory Acceptance Test package is included to support common GMP compliance documentation needs.

Evolve, expand, excel. The Thermo Scientific Vios iDx line of third-party certified, clean-room compatible CO2 incubators leverage all of the features previously outlined with our standard models. Designed for production of advanced therapies in ISO Class 5, GMP Grade A/B environments, scientists at the top of their field choose Vios iDx CR CO2 Incubators – CTS Series to achieve advanced incubation, and support their most demanding and critical applications, from research to discovery, development, and production scale-out.

Trustworthy, proven performance, and protection for sensitive cell cultures

• Thermo Scientific™ THRIVE™ active airflow technology for homogenous growth conditions and fast recovery of all parameters, minimizing the exposure of cell cultures to fluctuations and maintaining stable conditions with recovery of all parameters in ten minutes or less.
• Thermo Scientific™ Steri-Run™ high-temperature sterilization cycle is independently proven to provide a 12-log sterility assurance level and reaches 180°C in all areas, based on 48-point temperature mapping.
• In-chamber HEPA filtration achieves ISO Class 5 clean room-like air quality conditions within only five minutes after a 30-second door opening.
• IP54 rated electronics and sealed, brushed stainless steel exterior are certified cleanroom compatible to support your rigorous cleaning and disinfection protocols.
• Our exclusive particle control system protects your cleanroom by capturing particulates from the incubator through a rear-mounted HEPA filtration system.
• Proven compatible with common GMP facility protocols and cleanroom procedures including STERIS™ dry process systems using vaporized hydrogen peroxide (VHP) biodecontamination technology.
• Provided CTS Series factory acceptance test (FAT) documentation package with each unit includes everything you need for your audit: Regulatory certificatesRecommended protocols Certificates of conformance, calibration, sensor calibration, and technical specifications.Third-party certificate of compatibility with ISO Class 5 and GMP Grade A/B cleanroom environments.

Designs that are ready for where your discoveries take you

• IR180Si CO2 sensor for fast recovery and long service life.
• Condensation-free humidification system with protected, integrated 3-L water reservoir. Easily fill or drain without removing cultures to help keep sterilized distilled water clean. Slide out cover allows full access for cleaning.
• Large, crisp 7-in. touchscreen display for quicker at-a-glance monitoring of chamber conditions. Set language* and programmable access code provide additional accessibility and security.
• Ergonomic door design to make routine loading, unloading, and checking on cultures easier than ever. Electromagnetic door lock comes standard.
• Optional Active CO2 control functionality automatically adjusts levels, removing excess CO2 released by large-capacity cell culture systems to maintain the CO2 set point.
• Tri-gas options offer variable oxygen control for physiological tissue research. Simulate hypoxic (1-21% O2) or hyperoxic (5-90% O2) conditions based on application.
• Select electropolished stainless steel or 100% pure copper interior, with easy-to-clean curved interior chamber corners and shelving designs that are easy to install and remove without tools.
• Independently evaluated design for production of advanced therapies in ISO Class 5, GMP Grade A/B environments. Each individual unit is tested to prove compatibility.

Seamless operations in modern labs

• Connectivity-ready design with front access USB port, optional 4-20 mA signal output (factory installed option). Compatible with Connect Edge and OPCUA Gateway, and CellMation, making the Vios iDx CR compatible with common GMP facility protocols and procedures.
• Many factory installed and customer installed options and accessories are available, please review the product brochure for more information.
• Thermo Scientific™ Cell Locker™ Systems are available on the 165 L models to provide enhanced protection for valuable samples. Go to thermofisher.com/celllocker for more information.
• Thermo Scientific™ CultiMaxx™ Shelving Systems are customer installed accessories that offer increased culturing capacity on 255 L models. Go to thermofisher.com/cultimaxx for more information.

*Available user interface language options include English, Spanish, German, French, Italian, Japanese, and Mandarin. Specifications achieved under standard laboratory conditions at sea level, at a +22°C ambient condition, and nominal operating voltage. Other process conditions or ambient temperatures or altitude can affect performance. For example, a change of 2°C ambient temperature can influence the humidity by 1% rH.

Advanced CO₂ Incubation

Embark on the remarkable

Advanced incubation solutions enable the creation of novel cultures and therapies. Our most innovative CO2 Incubators offer designs that support groundbreaking science including: automated technologies, GMP and cleanroom requirements, and scale-up processes. View the comparison chart below to explore the features of all of our advanced CO2 incubators.

Designed for integration into automated laboratories

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Thermo Scientific Vios iDx AD 255 CO2 Incubators are designed for integration into automated laboratories that leverage a modular design to scale. The VIOS family of incubators are known for optimal cell growth conditions and minimal contamination risk. With the added innovation of a patent-pending automated door control, these leading incubators now bring their excellent recovery and uniformity to emerging automated cell therapy production processes 24/7, 365.

Many industry experts agree that human handling and complex processes limit broader application of cutting-edge cell therapies to treat cancer, autoimmunity, and orphan diseases. As automation is incorporated across the sector, these treatments can be produced in a more cost effective way. Several companies are developing advanced robotics to help meet these goals and Heracell VIOS 250i AxD CO2 Incubators are a natural fit. Various therapies are researched and developed in these incubators due to their excellent culturing conditions that help ensure important cellular critical quality attributes.

Cleanroom compatible CO₂ incubators

Thermo Scientific Vios iDx CR CO2 Incubators are third-party certified cleanroom compatible and suitable for ISO Class 5 and Good Manufacturing Practices (GMP) grade A/B environments. They feature an active particle control system and demonstrated compatibility with commonly used cleanroom cleaning methods, making it the exceptional fit for your cleanroom suite or GMP production environment.

Download our ebook Five Reasons to choose a cleanroom CO2 incubator that is certified compatible for an in-depth look at the advantages of using a CO2 incubator with cleanroom certification.

Features of
all cleanroom compatible incubators

Cleanroom certified

Through rigorous testing, the Vios iDx CR CO2 incubators have successfully achieved ISO class 5 compatibility for the considered particle sizes in both standard operating and sterilization modes.

Robust and easy to clean

• Brushed 304 stainless steel exterior is compatible with STERIS dry non-condensing VHP and 3% manual wipe hydrogen peroxide cleaning methods typically used in cleanroom environments.
• Sealed exterior casing includes silicone sealed electronics and welded door to contain any particulate risk.
• IP54 rated componentry protects electronics from dust and is resistant to water spray from any direction.

Documentation package including:

• Regulatory certificates
• Declaration of Conformity (CE) with EU law, CSA and QMS Certificates
• Recommended protocols
• User-replaceable parts and consumables lists
• Product-specific factory documentation and specification
• Certificates of conformance, calibration, and technical specifications
• 3rd party certificate of compatibility with ISO Class 5 and GMP Grade A/B cleanroom environments

Advanced CO2 Incubators Comparison

View all CO2 incubator specifications with the CO2 incubator selection guide

Scale-up with CultiMaxx Shelving Systems

As you scale out your cell therapy manufacturing, the incubator you have come to trust can now adjust with you. To match your changing needs, our special shelving system options offer additional capacity and/or improved access for specialized cell culture vessels such as Wilson Wolf G-Rex® 500M-CS bioreactors or Thermo Scientific Nunc Cell Factory systems.

These dedicated shelving systems are available as separate accessories. Each offers several advantages as you enter the cell expansion stage using larger cell culture vessels.

View options for Vios iDx CR, Steri-Cult, and Large Capacity Reach-In CO2 incubators

CultiMaxx Shelving for G-Rex Bioreactors, Nunc Cell Factory Systems and 1 L Culture Bags in Vios iDx CO2 Incubators.